A review on the application of marine Bioluminescence organism

Bioluminescence is a natural and fascinating phenomenon in which living organisms produce light by enzymatic activity. Over many years, researchers have been studying the genetic sequence, biochemical, and physiology of bioluminescent organisms. In nature, forty different bioluminescent systems are found in that seven light-emitting reactions are known, and only two chemical pathways have been studied completely. Bioluminescence is used for many purposes but in the last decade, it has been used tremendously in several advanced fields. The ability to isolate and transfer the lux genes in both prokaryotic and eukaryotic organisms has potentially made the use of bioluminescent bacteria. It is applied to detect protein-protein interaction, to check the efficiency of drugs, and biosensors to validate environmental pollution, immunology, oncology, neuroscience, the food industry, and so on. This paper will review the discoveries and current applications of marine bioluminescence organisms in the field of biosensors tagged with bioluminescent gene and their applications in various purposes, bioluminescent assay in food industries, and molecular methods, bioluminescent tagged gene and their potential in anti-cancer immunotherapy, bioluminescent imaging to detect the infected cells in animal model, and immunoassay applications of RLux gene extracted from Renilla reniformis.