Title of article
Bi(OTf)3 as a Highly Potent Catalyst for the Synthesis of Mannich Bases under Milder Conditions
Author/Authors
Udgire ، Somnath Dr. Arvind B. Telang Senior College of Arts, Science and Commerce , Gaikwad ، Milind Department of Chemistry - Dr. D. Y. Patil Arts, Commerce Science (ACS) College - Savitribai Phule Pune University , Patil ، Prakash Dr. Arvind B. Telang Senior College of Arts, Science and Commerce
From page
31
To page
39
Abstract
A simple, eco-friendly friendly and efficient procedure for the synthesis of Mannich Baseshas been developed via multi-component and one-pot reactions of various aldehydes with aniline, and acetophenone and catalytic amount of Bi(OTf)3 reagent in a DCM solvent.The Bi(OTf)3 acts as a highly potent catalyst ( 0.5 to 1 mol%) for a for the synthesis of Mannich base (1,3-diphenyl-3-(phenylamino)propan-1-one). This protocol is also compatible with a variety of hetero aldehyde carbonyl compounds in excellent yields. Thus, this practical method is developed as a notable medium for these derivatives via a multicomponent reaction.
Keywords
Bi(OTf)3 , One , pot three , component , Greener , Mannich reaction
Journal title
Journal of Applied Organometallic Chemistry
Journal title
Journal of Applied Organometallic Chemistry
Record number
2772116
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