Title of article
Use of Tranexamic Acid in SARS-COV-2: Boon or Bane?
Author/Authors
Chandela ، Manisha Department of Dermatology, Venereology and Leprosy - North DMC Medical College and Hindu Rao Hospital , Saxena ، Ashok K Department of Dermatology, Venereology and Leprosy - North DMC Medical College and Hindu Rao Hospital , Mehta ، RK Department of Dermatology, Venereology and Leprosy - North DMC Medical College and Hindu Rao Hospital , Mohanty ، Sandip Dermatology, Venereology and Leprosy - North DMC Medical College and Hindu Rao Hospital , Singla ، Pretty Department of Department of Dermatology, Venereology and Leprosy - North DMC Medical College and Hindu Rao Hospital , Solanki ، Aarushi Department of Dermatology, Venereology and Leprosy - North DMC Medical College and Hindu Rao Hospital , Jethani ، Sumit Department of Community Medicine - North DMC Medical College and Hindu Rao Hospital , Kamble ، Bhushan D Department of Community and Family Medicine - All India Institute of Medical Sciences (AIIMS) Bibinagar
From page
459
To page
464
Abstract
The devastating pandemic of SARS-CoV-2 (COVID-19) began in Wuhan, China, and spread rapidly through most parts of the world in the second half of 2020. The air droplet spread of SARS-CoV-2 is of great global health concern as it is potentially fatal. Various drugs and treatment modalities have been tried to date, but none have been found to be definitive. Tranexamic acid (TXA) is commonly used in pigmentary disorders in dermatology due to its ability to reduce melanocyte tyrosinase activity. It also possesses anti-fibrinolytic and anti-inflammatory properties, which have been observed to suppress the cytokine storm and modulate coagulopathy in patients suffering from COVID-19. TXA, when administered early, has been effective in decreasing the severity of symptoms in COVID-19 patients, but on the contrary, it has also been associated with life-threatening thrombosis when given as a single drug.
Keywords
COVID , 19 , SARS , CoV , 2 , Tranexamic acid
Journal title
Archives of Razi Institute
Journal title
Archives of Razi Institute
Record number
2772375
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