Title of article :
Systematic review and meta-analysis of narcolepsy management during the covid-19 pandemic
Author/Authors :
Deylami ، Mansour Department of Anesthesiology and Critical Care - Faculty of Medicine - Golestan University of Medical Sciences , Vatankhah ، Majid Critical Care and Management Research Center - Hormozgan University of Medical Sciences , Zarei ، Tayyebeh Critical Care and Management Research Center - Hormozgan University of Medical Sciences , Rahmanian ، Ehsan Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Javdani ، Farshid Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Shafa ، Shahram Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Zabetian ، Hasan Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Najar Nobari ، Minou Orofacial Pain and Dysfunction and Sleep Disorders Department - School of Dentistry - University of California, Los Angeles , Hedayati Emami ، Kaveh Department of Anesthesiology and Critical Care - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences , Maleki ، Fatemeh Department of Emergency Medicine - Faculty of Medicine - Birjand University of Medical Sciences , Shafiei ، Amin Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Hafezi ، Vida Student Research Committee - Alborz University of Medical Sciences , Farzaneh ، Roohie Department of Emergency Medicine - Faculty of Medicine - Mashhad University of Medical sciences , Sanie Jahromi ، Mohammad Sadegh Research Center for Social Determinants of Health - Jahrom University of Medical Sciences
Abstract :
The concern has recently been raised for disease status and management of people with narcolepsy after initiation of COVID-19 pandemic. Here, we evaluated the literature to determine how the COVID-19 pandemic has impacted the lives of narcolepsy patients. This was a systematic review and meta-analysis study on online databases of Web of Science, PubMed, Scopus, and ScienceDirect using keywords of “Narcolepsy”, “Sleepiness “, “cataplexy”, “nightmare”, “nocturnal sleep”, “COVID-19”, “Pandemic”, “SARS-COV2”, and “Coronavirus”, looking for observational studies. Statistical analyses were performed by CAM software with significance level being considered at under 0.05 as statistically significant. Total number of 9 studies were included with 607 patients with narcolepsy. With a heterogeneity of 99.94%, pooled mean differences (MD) of Epworth Sleepiness Scale (ESS) scores before and after the pandemic/lockdowns was -1.54 (95%CI: -1.55 to -1.53, P 0.01). The most prevalently increased symptom among the narcolepsy patients was naps taken during the day (58.81%, 95%CI of 50.85 to 66.34) followed by the increased appetite (45.15%, 95%CI of 28.91 to 62.49). Our study shows that disease status of narcolepsy patients is affected by COVID-19 pandemic. We can assist narcolepsy patients in this challenging position by being aware of their unique demands during the COVID-19 illness and sympathetic to their sensitivity.
Keywords :
COVID , 19 , narcolepsy , Meta , analysis , sleep , Pandemic
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
