Title of article
Systematic review and meta-analysis of narcolepsy management during the covid-19 pandemic
Author/Authors
Deylami ، Mansour Department of Anesthesiology and Critical Care - Faculty of Medicine - Golestan University of Medical Sciences , Vatankhah ، Majid Critical Care and Management Research Center - Hormozgan University of Medical Sciences , Zarei ، Tayyebeh Critical Care and Management Research Center - Hormozgan University of Medical Sciences , Rahmanian ، Ehsan Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Javdani ، Farshid Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Shafa ، Shahram Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Zabetian ، Hasan Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Najar Nobari ، Minou Orofacial Pain and Dysfunction and Sleep Disorders Department - School of Dentistry - University of California, Los Angeles , Hedayati Emami ، Kaveh Department of Anesthesiology and Critical Care - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences , Maleki ، Fatemeh Department of Emergency Medicine - Faculty of Medicine - Birjand University of Medical Sciences , Shafiei ، Amin Research Center for Social Determinants of Health - Jahrom University of Medical Sciences , Hafezi ، Vida Student Research Committee - Alborz University of Medical Sciences , Farzaneh ، Roohie Department of Emergency Medicine - Faculty of Medicine - Mashhad University of Medical sciences , Sanie Jahromi ، Mohammad Sadegh Research Center for Social Determinants of Health - Jahrom University of Medical Sciences
From page
292
To page
301
Abstract
The concern has recently been raised for disease status and management of people with narcolepsy after initiation of COVID-19 pandemic. Here, we evaluated the literature to determine how the COVID-19 pandemic has impacted the lives of narcolepsy patients. This was a systematic review and meta-analysis study on online databases of Web of Science, PubMed, Scopus, and ScienceDirect using keywords of “Narcolepsy”, “Sleepiness “, “cataplexy”, “nightmare”, “nocturnal sleep”, “COVID-19”, “Pandemic”, “SARS-COV2”, and “Coronavirus”, looking for observational studies. Statistical analyses were performed by CAM software with significance level being considered at under 0.05 as statistically significant. Total number of 9 studies were included with 607 patients with narcolepsy. With a heterogeneity of 99.94%, pooled mean differences (MD) of Epworth Sleepiness Scale (ESS) scores before and after the pandemic/lockdowns was -1.54 (95%CI: -1.55 to -1.53, P 0.01). The most prevalently increased symptom among the narcolepsy patients was naps taken during the day (58.81%, 95%CI of 50.85 to 66.34) followed by the increased appetite (45.15%, 95%CI of 28.91 to 62.49). Our study shows that disease status of narcolepsy patients is affected by COVID-19 pandemic. We can assist narcolepsy patients in this challenging position by being aware of their unique demands during the COVID-19 illness and sympathetic to their sensitivity.
Keywords
COVID , 19 , narcolepsy , Meta , analysis , sleep , Pandemic
Journal title
Eurasian Chemical Communications
Journal title
Eurasian Chemical Communications
Record number
2775286
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