Title of article
Nephrotic Syndrome and Recurrent Infection
Author/Authors
Shahraki ghadimi ، Zahra Clinical Immunology Research Center - Zahedan University of Medical Sciences , Sadeghi Bojd ، Simin Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Ali Ibne Abitaleb Hospital - Zahedan University of Medical Sciences , Parvaneh ، Nima Research Center for Immunodeficiencies, Childrens Medical Center Hospital - Tehran University of Medical Sciences , Atabaki ، Mehdi Clinical Immunology Research Center - Zahedan University of Medical Sciences , Alijani ، Ebrahim Clinical Immunology Research Center - Zahedan University of Medical Sciences
From page
594
To page
599
Abstract
Nephrotic syndrome is characterized by the leakage of protein from the blood into the urine along with the triad of proteinuria, albuminuria, and peripheral edema. Loss of protein leads to the loss of immunoglobulin and complements. X-linked agammaglobulinemia (XLA), or Bruton disease, is a primary immunodeficiency disease caused by a defect in the development of B cells in the bone marrow and a low serum level of immunoglobulins. The present case involves a 12-year-old boy with nephrotic syndrome, osteomyelitis, and recurrent infections. We discovered that he had XLA. This report underscores the importance of considering inborn errors of immunity in cases of protein loss, such as nephrotic syndrome.
Keywords
Bruton type agammaglobulinemia , Inborn errors of immunity , Nephrotic syndrome , Primary immunodeficiency diseases , X , linked agammaglobulinemia
Journal title
Iranian Journal of Allergy, Asthma and Immunology
Journal title
Iranian Journal of Allergy, Asthma and Immunology
Record number
2778086
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