Abstract :
This study was conducted to investigate the effect of contraceptive drugs on some of the physiological parameters of the thyroid gland and its relation to fertility standards of male rats and on triglycerides, lipoproteins, follicle stimulation hormone, and cholesterol levels in the blood. The animals were divided into 3 groups, (1) the control group, (2) T2, administered 0.32mg of levonorgestrel and (3) T3, administer 0.64mg orally for 2 months. The fertility of rats was estimated by administrating 3 females for each male and calculating the number of fetuses and pregnancies. The results showed decreased male desire and mating for females in the T1 and T2 groups. The testosterone and cholesterol testes in the fetuses showed some of them mutilated, and some pre-emptive and some less than normal. Fetuses of the T1 were not different from normal control. At the end of the experiment, animals were killed and dissected, and blood and sample were collected. The level of the T4 increased compared to the control one. In addition, increasing the blood triglycerides in the T2 and decreasing the level in T2 compared to the control were recorded. Decreasing in high-density lipoproteins was also recorded. The results also showed a significant reduction in the sperm and distortion sperm with a significant decrease in the hormone levels of the male (P 0.05clearly affected that the pills have a clear effect on males fertility, causing a pathological hormonal imbalance that can negatively affect the ability of male fertilization.
Keywords :
Contraceptive , Male , Lipoproteins , Fertility
