Comparison of Chemotherapy Effectiveness Between Cancer Patients with and without Dependent Dose of Radiotherapy

Aims: Cancer is now known to be one of the most important health issues people face. So, we looked into what makes cancer grow. This research aimed to compare the effect of chemotherapy in the presence and absence of radiotherapy in cancer patients. Materials Methods: In this experimental study, which took place at Al-Hussein Teaching Hospital in Kerbala from October 2023 to February 2024, 94 cancer patients between 30 and 50 years old were divided into two radiotherapy (n=48) and non-radiotherapy (n=46) groups according to the expert’s opinion. An enzyme-linked immunosorbent assay was used to identify serum tumor markers. Spectrophotometric analysis was used to detect calcium and phosphorus levels in the sera. The data were evaluated using the student’s t-test in SPSS 26 software. Findings: There were significant differences in CA15-3, AFP, and CA19-9, calcitonin, carcinoembryonic antigen, calcium, and phosphorus levels between the chemotherapy and non-chemotherapy groups. Conclusion: Using chemotherapy alone is not enough to treat cancer, and it makes the cancer spread when used without radiation treatment. To save the bone, chemotherapy must be used with dose-dependent radiation.