Author/Authors :
Rahmani ، Erfan School of Medicine - Tehran University of Medical Sciences , Fayyazishishavan ، Ehsan Department of Biostatistics and Data Science - School of Public Health - University of Texas Health Science Center at Houston (UTHealth) , Afzalian ، Arian School of Medicine - Tehran University of Medical Sciences , Varshochi ، Sanaz School of Medicine - Tehran University of Medical Sciences , Amani-Beni ، Reza School of Medicine - Isfahan University of Medical Sciences , Ahadiat ، Amirabbas Girona University , Moshtaghi ، Zeynab Faculty of Nursing - Bushehr University of Medical Sciences , Shafagh ، Ghavam School of Medicine - Iran University of Medical Sciences , Khorram ، Roya Center, Department of Orthopedic Surgery - Bone and Joint Diseases Research Center - Shiraz University of Medical Sciences , Asadollahzade ، Elnaz Multiple Sclerosis Research Center, Neuroscience Institute - Tehran University of Medical Sciences , Atbaei ، Raihaneh School of Medicine - Jahrom University of Medical Sciences , Kahrizi ، Mohammad Saeed School of Medicine - Alborz University of Medical Sciences , Rahbari ، Atoosa Islamic Azad University, Tehran Medical Branch , Baharlouie ، Negar School of Medicine - Isfahan University of Medical Sciences , Mostanbet ، Farzaneh School of Medicine - Shiraz University of Medical Sciences , Amirabadiquchani ، Bahamin Mashhad University of Medical Sciences , Kiani ، Moein School of Medicine - Zanjan University of Medical Sciences , Memarizadeh ، Mozhdeh School of Medicine - Shiraz University of Medical Sciences , Keshtkar Rajabi ، Shahin Firoozabadi hospital clinical research development unit (FHCRDU), Department of internal medicine - school of medicine - Iran University of Medical Sciences (IUMS) , Barati ، Reza School of Medicine - Iran University of Medical Sciences , Hajinouri ، Hengame School of Medicine - Islamic Azad University, Tehran Branch , Najafi ، Shahrzad School of Medicine - Tehran University of Medical Sciences , Abdollahi ، Zeynab Department of Radiology - School of Medicine - Ahvaz Jundishapur University of Medical Sciences , Dadashzadehasl ، Nahid Legal Medicine Research Center - Iranian Legal Medicine Organization , Moghadam Fard ، Atousa ERIS Research Institute , Afshar ، Mozhgan Islamic Azad University, South Tehran Branch , Abedi ، Atefeh Dental and Periodontal Research Center - Tabriz University of Medical Sciences , Saeidi ، Sara Students Research Committee, Faculty of Pharmacy and Pharmaceutical Sciences - Isfahan University of Medical Sciences , Mansourirad ، Adeleh Herman Ostrow School of Dentistry - University of Southern California , Emami Sharezaei ، Pedram Islamic Azad University, Najafabad Branch , Shah Hosseini ، Sepideh School of Medicine - Iran University of Medical Sciences , Rostami Ghotbabadi ، Zahra School of Medicine - Shiraz University of Medical Sciences , Vafadar ، Reza Department of Orthopedic Surgery - Kerman University of Medical Sciences , Roohinezhad ، Roozbeh School of Medicine - Iran University of Medical Sciences , Ghalamkarpour ، Nogol Department of Clinical Laboratory Sciences - School of Allied Medicine, Student Research Committee - Lorestan University of Medical Sciences , Farrokhi ، Mehrdad ERIS Research Institute
Abstract :
Introduction: Differentiating the soft tissue abscess from other types of skin and soft tissue infections (SSTIs) poses a particular challenge because they have similar physical evaluation findings, but each disease has a different course, outcome, and treatment. This meta-analysis aimed to investigate the diagnostic accuracy of point-of-care ultrasonography for diagnosis of soft tissue abscess in the emergency departments. Methods: A comprehensive literature search of MEDLINE, Scopus, Web of Science, Embase, and Google Scholar, from inception to January 2023, was conducted to identify relevant studies investigating the diagnostic performance of point-of-care ultrasonography for identification of abscess. Methodological quality of the included studies was assessed using a revised tool for the quality assessment of diagnostic accuracy studies (QUADAS-2). Results: The pooled estimates of diagnostic parameters of ultrasonography for diagnosis of abscess were as follows: sensitivity, 0.93 (95% CI: 0.92–0.94); specificity, 0.87 (95% CI: 0.85–0.89), and the area under the summary receiver-operating characteristic (SROC), 0.95. The pooled sensitivity, specificity, and area under the SROC of studies in adult patients were 0.98 (95% CI: 0.92–1), 0.92 (95% CI: 0.86–0.95), and 0.99, respectively. The pooled sensitivity, specificity, and area under the SROC of studies in pediatric patients were 0.9 (95% CI: 0.87–0.92), 0.78 (95% CI: 0.73–0.82), and 0.91, respectively. Conclusion: Our meta-analysis demonstrated that the point-of-care ultrasonography has excellent diagnostic value for the abscess in the emergency department. Furthermore, we found that the diagnostic performance of point-of-care ultrasonography for diagnosis of abscess was higher for adult cases than for pediatric patients.
Keywords :
Abscess , cellulitis , diagnostic imaging , meta , analysis , ultrasonography