Surface Plasmon Resonance Detector for Capillary Chip Electrophoresis

A novel universal detection system for capillary chip electrophoresis utilizing surface plasmon resonance (SPR) detection was developed. Nafion tube was used as a septum to draw electric current outside the flow without generating any bubble in the capillary channel. Polydimethyl siloxane as a capillary chip could easily attained this setup. We could successfully observe small change in refractive index by SPR under elctroosmotic flow.