Title of article
Selective Binding and Cleavage of DNA by Stereoisomers of N,N-Bis (phenanthrolin-2-yl)-1,2-cyclohexanediamine Conjugates, and Their Copper Complexes
Author/Authors
Ozaki، Hiroaki نويسنده , , Sawai، Hiroaki نويسنده , , Hayashi، Keigo نويسنده , , Nakajima، Ryouko نويسنده , , Kiyosawa، Isao نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-683
From page
684
To page
0
Abstract
Stereoisomers, trans-RR, trans-SS, and cis forms, of N,Nʹ-bis(phenanthrolin-2-yl)-1,2-cyclohexanediamine conjugates were prepared, and their DNA binding activity was evaluated. The copper complexes of the conjugates (ligand:Cu(II) = 1:1 and 1:2) cleave DNA in the same order of the DNA binding activity of the conjugates, trans-RR > cis > trans-SS.
Keywords
Application-production research , prediction , Surface finish , Power requirement , Genetic-fuzzy system , grinding
Journal title
CHEMISTRY LETTERS
Serial Year
2004
Journal title
CHEMISTRY LETTERS
Record number
28384
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