Synthesis and Characterization of an Iron Porphyrin with a Thiolate Axial Ligand and Its Dioxygen Adduct as a Model for the Active Center of Cytochrome P-450

Synthesis and characterization of an iron porphyrin axiallycoordinated by thiolate were carried out in order to mimic the active center of cytochrome P-450. 02 binds reversibly to the ferrous form at -80 °C. The oxygenated complex showed a v(Fe-O2) band at 578 cm in the resonance Raman spectrum.