Synthesis of 18-Demethyltaxoid via Stereoselective Allylation and Intramolecular Aldol Condensation Reactions

A water-soluble C60-terminating ammonium surfactant, 1, was synthesized. Electron microscopy revealed that 1 forms a fibrous aggregate in an aqueous solution. Electronic interaction between the fullerene moieties in 1 in the aqueous solution was observed. Electrochemistry for 1 aqueous solutions was found to be quite different from that of 1 in the film states.