Title of article :
Noncovalent Combination of Oligoamine and Oligonucleotide as Totally Organic Site-selective RNA Cutter
Author/Authors :
Komiyama، Makoto نويسنده , , Kuzuya، Akinori نويسنده , , Shi، Yun نويسنده , , Niikura، Fumiya نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
When a one-base gap was formed in substrate RNA by using two oligonucleotides, the phosphodiester linkage at the gap-site was activated and selectively hydrolyzed by ethylenediamine. This site-selective hydrolysis was further promoted by connecting two gap-forming oligonucleotides with 1,3-propanediol linker.
Keywords :
Surface finish , Power requirement , Application-production research , Genetic-fuzzy system , prediction , grinding
Journal title :
CHEMISTRY LETTERS
Journal title :
CHEMISTRY LETTERS