Title of article
Stereoselective Synthesis of 19-Hydroxytaxoid Using Intramolecular Pinacol Coupling Reaction
Author/Authors
Mukaiyama، Teruaki نويسنده , , Matsuo، Jun-ichi نويسنده , , Ogawa، Yasuyuki نويسنده , , Kuroda، Kiichi نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-1411
From page
1412
To page
0
Abstract
The ABC-ring system of 19-hydroxytaxol is stereoselectively constructed by intramolecular pinacol coupling of diketone 12 with low valent titanium species prepared from TiCl2 and LiAlH4. After manipulations of hydroxy protecting groups, a new 19-hydroxytaxoid 18 was afforded by olefination of vicinal diol part of 17.
Keywords
Application-production research , Genetic-fuzzy system , Surface finish , Power requirement , grinding , prediction
Journal title
CHEMISTRY LETTERS
Serial Year
2004
Journal title
CHEMISTRY LETTERS
Record number
28861
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