Quantitative radiography in osteoarthritis: Microfocal radiography

Quantitative macroradiography of patients with hand and knee OA, employing standardized radiographic and mensural procedures, permit: • accurate and reproducible measurements of all radiographic features. • significant changes in JSW and osteophyte number and size to be detected within as short a period as 18 months. • therapeutic effects upon articular cartilage to be determined from changes in JSW. • a better understanding of the disease process from an evaluation of the relative changes in the different radiographic features of OA.