Allogeneic transplantation of peripheral blood stem cells

Mobilized peripheral blood stem cells (PBSC) are increasingly being used instead of bone marrow for allogeneic transplantation. This chapter will briefly review important aspects of allogeneic PBSC transplantation including PBSC harvesting and donor safety, reconstitution of haematopoiesis and the immune system, graft-versus-host disease, graft-versus-leukaemia effects and graft engineering