Title of article :
Disseminated intravascular coagulation and purpura fulminans secondary to infection
Author/Authors :
Saul N. Faust، نويسنده , , Robert S. Heyderman، نويسنده , , Stephen Michael Levin، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.
Keywords :
pathophysiology , Gram-negative , clinical trials , Therapy , disseminated intravascular coagulation (DIC) , purpura fulminans , meningococcal , tissue factor (TF) , tissue factor pathwayinhibitor (TFPI) , antithrombin (ATIII) , thrombomodulin (TM) , protein C (PC)/activated proteinC (APC) , tissue plasminogen activator (tPA).
Journal title :
Best Practice and Research Clinical Haematology
Journal title :
Best Practice and Research Clinical Haematology
