Author/Authors :
Bali Pulendran، نويسنده , , Jacques Banchereau، نويسنده , , Eugene Maraskovsky، نويسنده , , Charles Maliszewski، نويسنده ,
Abstract :
Different subsets of dendritic cells (DCs) appear to play a role in determining the specific cytokines secreted by T helper (Th) cells. A model is proposed that links together factors such as the pathogen, microenvironment, DCs and T cells in a mechanism that results in a flexible determination of T-cell polarization.