Role of fucosyltransferases in leukocyte trafficking: major impact for cutaneous immunity

Recent papers on the role of fucosyltransferase VII (FucTVII) in leukocyte trafficking underscore the importance of this glycosyltransferase for selectin ligand synthesis, inflammation and skin homing. Furthermore, other data have shown how another transferase, FucTIV, might compensate for FucTVII functions and contribute to the generation of functional binding epitopes involved in tethering and rolling functions.