Objectives
To evaluate the feasibility of noninvasive assessment of the characteristics of disrupted atherosclerotic plaques, the authors interrogated the culprit lesions in acute coronary syndromes (ACS) by multislice computed tomography (CT).
Background
Disrupted atherosclerotic plaques responsible for ACS histopathologically demonstrate large lipid cores and positive vascular remodeling. It is expected that plaques vulnerable to rupture should bear similar imaging signatures by CT.
Methods
Either 0.5-mm × 16-slice or 64-slice CT was performed in 38 patients with ACS and compared with 33 patients with stable angina pectoris (SAP) before percutaneous coronary intervention. The coronary plaques in ACS and SAP were evaluated for the CT plaque characteristics, including vessel remodeling, consistency of noncalcified plaque (NCP <30 HU or 30 HU
Keywords :
computed tomography , CT , PCI , Coronary Angiography , SAP , ECG , Electrocardiogram , NPV , IVUS , Percutaneous coronary intervention , Acute coronary syndrome , PPV , intravascular ultrasound , ACS , NSTEMI , STEMI , ST-segment elevation myocardial infarction , CAG , UAP , MSCT , positive predictive value , non–ST-segment elevation myocardial infarction , stable angina pectoris , multislice computed tomography , TCFA , NCP , thin cap fibroatheroma , noncalcified plaques , negative predictive values , unstable