The cortico-basal ganglia-thalamocortical circuit with synaptic plasticity. II. Mechanism of synergistic modulation of thalamic activity via the direct and indirect pathways through the basal ganglia

We use the recent reanalysis of multi-TeV gamma-ray observations of Mrk 501 to constrain the Lorentz invariance breaking parameter involving the maximum electron velocity. Our limit is two orders of magnitude better than that obtained from the maximum observed cosmic-ray electron energy.