Author/Authors :
Jean-louis Beaudeux، نويسنده , , Richard Dorent، نويسنده , , Maguy Bernard، نويسنده , , Mary Reagan، نويسنده , , Marie-José Foglietti، نويسنده , , Iradj Gandjbakhch، نويسنده , , Patrice Cacoub، نويسنده ,
Abstract :
Objective: To evaluate serum Monocyte Chemoattractant Protein-1 (MCP-1) as a biologic marker of cardiac allograft vasculopathy (CAV) in heart transplant recipients (HTR).
Design and methods: Serum levels of MCP-1 were measured in 49 HTR with and without CAV.
Results: HTR exhibited significantly higher serum MCP-1 levels than controls. However, no difference was observed according to the existence of CAV.
Conclusion: Serum MCP-1 levels do not constitute a marker of the CAV occurring after heart transplantation.
Keywords :
adhesion molecules , Heart transplantation , Monocyte chemoattractant protein-1 , cardiac allograft vasculopathy , Selectins
