• Title of article

    Measurement of lysophospholipase D/autotaxin activity in human serum samples

  • Author/Authors

    Kazuhiro Nakamura، نويسنده , , Ryunosuke Ohkawa، نويسنده , , Shigeo Okubo، نويسنده , , Minoru Tozuka، نويسنده , , Mitsumasa Okada، نويسنده , , Shinya Aoki، نويسنده , , Junken Aoki، نويسنده , , Hiroyuki Arai، نويسنده , , Hitoshi Ikeda، نويسنده , , Yutaka Yatomi، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2007
  • Pages
    4
  • From page
    274
  • To page
    277
  • Abstract
    Objectives: Lysophospholipase D (lysoPLD)/autotaxin regulates the blood levels of lysophosphatidic acid (LPA), and we designed a serum lysoPLD assay for use in clinical laboratory testing. Design and methods: LysoPLD activity was assessed based on the amount of choline released with lysophosphatidylcholine as the substrate. Results and conclusions: It was confirmed that the lysoPLD assay can be applied to clinical laboratory testing. The serum lysoPLD activity in healthy female subjects was significantly higher than that in the male subjects.
  • Keywords
    lysophosphatidylcholine , Plasma , Lysophospholipase D , Autotaxin , Lysophosphatidic acid
  • Journal title
    Clinical Biochemistry
  • Serial Year
    2007
  • Journal title
    Clinical Biochemistry
  • Record number

    484897