Analytical interferences of drugs in the chemical examination of urinary protein

Objectives: To evaluate the potential analytical interference of 24 drugs in the urinary protein. Design and methods: The analysis was done using Multistix® 10SG and comparing the results of controls with urine samples supplemented with drugs. Results: Positive interferences occurred with ciprofloxacin, quinine and chloroquine in supratherapeutical concentrations, while chloroquine interfered also in therapeutical concentration. Conclusions: False proteinuria in test-strips can lead to erroneous interpretations with repercussion in clinical procedures and higher costs to the health system.