• Title of article

    Performance evaluation of ion exchange and affinity chromatography for HbA1c estimation in diabetic patients with HbD: A study of 129 samples

  • Author/Authors

    Bushra Moiz، نويسنده , , Mashhooda Rasool Hashmi، نويسنده , , Shahmina Sadaf، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2008
  • Pages
    7
  • From page
    1204
  • To page
    1210
  • Abstract
    Objectives To compare ion exchange and boronate affinity chromatography for HbA1c estimation in patients with type I and II diabetes having hemoglobin D. Design and methods Systems based on ion exchange and boronate affinity chromatography were evaluated and compared for their performance for HbA1c estimation in patients with homozygous and heterozygous D disease. Results Boronate affinity chromatography shows least interference by HbD in heterozygous as well as homozygous diabetic patients for HbA1c estimation. Conclusions The use of boronate affinity chromatography was found to be helpful in evaluating glycemic control in diabetic subjects with HbD.
  • Keywords
    HBA1C , Diabetes , chromatography , HbD , Hemoglobin variant
  • Journal title
    Clinical Biochemistry
  • Serial Year
    2008
  • Journal title
    Clinical Biochemistry
  • Record number

    485270