Title of article :
Lamotrigine in two cases of Rett syndrome
Author/Authors :
Sefer Kumandas، نويسنده , , Hüseyin Caksen، نويسنده , , Ahmet Ciftçi، نويسنده , , Mustafa ?ztürk، نويسنده , , Hüseyin Per، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Pages :
3
From page :
240
To page :
242
Abstract :
Rett syndrome (RS) is a particular neurodevelopmental disorder in which symptoms develop in early infancy and manifests particular symptoms at certain ages. Two girls aged 4.5 and 2.5-years-old were admitted with complaints of seizures, regression of language, psychomotor development, and autistic behavior. They had fulfilled the criteria of classic RS. Lamotrigine was used in the treatment of the convulsions. After lamotrigine therapy, the convulsions were successfully controlled and the stereotyped hand movements and autistic behaviors markedly decreased. We would like to stress that, aside from convulsion, abnormal signs of the syndrome such as stereotyped hand movements and autistic behaviors might also be improved with lamotrigine, but detailed and controlled studies should be performed to identify whether lamotrigine has any positive effects in RS.
Keywords :
Rett syndrome , lamotrigine
Journal title :
Brain and Development
Serial Year :
2001
Journal title :
Brain and Development
Record number :
494369
Link To Document :
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