Title of article
Advantages of the CBA Mouse in Leukemogenesis Research,
Author/Authors
K. Noy Rithidech، نويسنده , , E. P. Cronkite، نويسنده , , V. P. Bond، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
8
From page
38
To page
45
Abstract
ABSTRACT: The objectives of this review are to: (a) demonstrate that the male CBA/Ca mouse has several characteristics that make it an excellent animal for the study of leukemogenesis, (b) show that several of the genetic abnormalities observed in the male CBA/Ca mouse during the development of radiation induced acute myeloid leukemia (AML) are syntenic with those frequently detected in patients with myeloid disorders such as myelodysplastic syndrome and AML, (c) illustrate that leukemia-related chromosomal lesions are the indicators for high risk individuals
Keywords
cytogenetics , radiation , Benzene , Leukemogenesis
Journal title
Blood Cells, Molecules and Diseases
Serial Year
1999
Journal title
Blood Cells, Molecules and Diseases
Record number
498248
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