Author/Authors :
M.P. Gallegos-Arreola، نويسنده , , C.M. Batista-Gonzalez، نويسنده , , J.L. Delgado-Lamas، نويسنده , , L.E. Figuera، نويسنده , , A.M. Puebla-Perez، نويسنده , , L. Arnaud-Lopez، نويسنده , , V. Peralta-Leal، نويسنده , , L.J. Ram?rez-Jirano، نويسنده , , G.M. Z?niga-Gonzalez، نويسنده ,
Abstract :
We studied the role of cytochrome P4501A1 (CYP1A1 Val/Val) genotypes in the etiology of acute lymphoblastic leukemia (ALL) in adult Mexican patients. Distributions of CYP1A1 Val/Val genotypes in peripheral blood DNA samples from 136 healthy controls and 136 adult patients with ALL were evaluated. There was an increased frequency of the CYP1A1 Val/Val genotype among ALL patients, showing a significant association between this genotype and the risk of developing ALL.
Keywords :
CYP1A1 , acute lymphoblastic leukemia , Polymorphism , Mexican population
