Author/Authors :
Stockle، Raout نويسنده , , Setz، Patrick نويسنده , , Deckert، Volker نويسنده , , Lippert، Thomas نويسنده , , Wokaun، Alexander نويسنده , , Zenobi، Renato نويسنده ,
Abstract :
We describe an atmospheric pressure nanosaropling interface for mass apectrometry based on near-field laser ablation. Pulsed laser radiation is delivered to the sample surface through a near-field optical probe, and the ablation plume is sampled through a capillary orifice and analyzed by standard MS methods. A spatial resolution of less than 200 nm and a sensitivity below 2 amol is demonstrated.
