Title of article :
Predictors of axillary lymph node metastasis in breast cancer: A systematic review
Author/Authors :
N.R. Patani، نويسنده , , M.V. Dwek، نويسنده , , M. Douek، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
11
From page :
409
To page :
419
Abstract :
Aims To review the established and emerging techniques in axillary lymph node prediction and explore their potential impact on clinical practice. To reliably identify patients in whom axillary lymph node surgery, including SLNB, can be safely omitted. Methods Searches of PubMed were made using the search terms “axilla” (or “axillary”), “lymph”, “node” and “predictor” (or “prediction”). Articles from abstracts and reports from meetings were included only when they related directly to previously published work. Findings There are numerous studies in which the predictive utility of biomarkers as determinants of axillary lymph node status have been investigated. Few of these have specifically addressed the attributes of the primary tumour which could offer much potential for the prediction of tumour metastasis to the axillary lymph nodes. Conclusions Currently, no single marker is sufficiently accurate to obviate the need for formal axillary staging using SLNB or axillary clearance.
Keywords :
prognosis , Axillary lymph node , Sentinel lymph node , lectin , Glycoprotein , predictor , Glycosylation
Journal title :
European Journal of Surgical Oncology
Serial Year :
2007
Journal title :
European Journal of Surgical Oncology
Record number :
511396
Link To Document :
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