Author/Authors :
Terry B Strom، نويسنده , , Prabir Roy-Chaudhury، نويسنده , , Roberto Manfro، نويسنده , , Xin Xiao Xheng، نويسنده , , Peter W Nickerson، نويسنده , , Kathryn Wood، نويسنده , , AndrewBushell، نويسنده ,
Abstract :
Although Th1- and Th2-type cytokine profiles have been associated with rejection and tolerance respectively, this paradigm may not be completely accurate. Instead, recent studies suggest that there could be a hierarchy of T-cell growth factors with regard to their ability to block tolerance and induce rejection (rather than a polarized Th1/Th2 demarcation).