Title of article :
Manipulation of the Th1/Th2 balance in autoimmune disease
Author/Authors :
Lindsay B Nicholson، نويسنده , , Vijay K Kuchroo، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Pages :
6
From page :
837
To page :
842
Abstract :
Many autoimmune diseases are caused by autopathogenic Th1 cells. Because in vitro Th1 and Th2 cells cross-regulate each other, it is likely that the induction of self-antigen-specific Th2 cells can prevent autoimmune disease. In the past year, investigators have further defined the role of Th1 and Th2 cytokines in the induction and regulation of autoimmunity. Furthermore, the role of MHC—antigen—T-cell avidity (strength of signal) in inducing such protective immune responses has been elucidated.
Journal title :
Current Opinion in Immunology
Serial Year :
1996
Journal title :
Current Opinion in Immunology
Record number :
511574
Link To Document :
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