• Title of article

    Pleiotropic changes controlled by the pre-T-cell receptor

  • Author/Authors

    Harald von Boehmer، نويسنده , , Iannis Aifantis، نويسنده , , Jacqueline Feinberg، نويسنده , , Oskar Lechner، نويسنده , , Claude Saint-Ruf، نويسنده , , Ulrich Walter، نويسنده , , Jan Buer، نويسنده , , Orly Azogui، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    8
  • From page
    135
  • To page
    142
  • Abstract
    The construction of various gene-deficient mice has facilitated the understanding of the role of various receptors and signaling pathways that control the generation of αβ lineage cells. A predominant role is occupied by the pre-TCR, which not only generates large numbers of a lineage cells but also controls TCRβ allelic exclusion as well as commitment to the γδ lineage versus the a lineage.
  • Journal title
    Current Opinion in Immunology
  • Serial Year
    1999
  • Journal title
    Current Opinion in Immunology
  • Record number

    511820