Title of article :
Tec kinases: modulators of lymphocyte signaling and development
Author/Authors :
Carol MacKinnon-Lewis، نويسنده , , Christine Broussard، نويسنده , , Michael J Czar، نويسنده , , Pamela L Schwartzberg، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes containing LAT and SLP-76 in T cells, and BLNK/SLP-65 in B cells, which are required for activation of PLC-γ and downstream pathways.
Journal title :
Current Opinion in Immunology
Journal title :
Current Opinion in Immunology