Isolation and identification of a phenolic antioxidant from Aloe barbadensis

A potent antioxidative compound has been isolated from a methanolic extract of Aloe barbadensis Miller using a combination of column and thin-layer chromatography. The antioxidant activity of this substance was similar to that of α-tocopherol as assessed in vitro using rat brain homogenates. On the basis of electrospray ionization and electron-impact ionization mass spectra in combination with reversed-phase, high-performance liquid chromatographic behavior, this compound has been identified as 8-C-β-image-[2-O-(E)-coumaroyl]glucopyranosyl-2-[2-hydroxy]propyl-7-methoxy-5-methylchromone.