Title of article
Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats
Author/Authors
Seigo Baba، نويسنده , , Naomi Osakabe، نويسنده , , Midori Natsume، نويسنده , , Junji Terao، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
7
From page
142
To page
148
Abstract
We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. After procyanidin B2 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (−)-epicatechin and to the metabolized conjugated and/or methylated (−)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions.
Keywords
Absorption , Urinary excretion , conjugation , degradation , rats , free radicals , Procyanidin B2 , Methylation , antioxidant , (?)-Epicatechin
Journal title
Free Radical Biology and Medicine
Serial Year
2002
Journal title
Free Radical Biology and Medicine
Record number
519197
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