Preparation of O-acylated low-molecular-weight carrageenans with potent anti-HIV activity and low anticoagulant effect

Molecular modeling calculations support assignment of the circular dichroism (CD) of unsubstituted saccharides and polysaccharides to oxygen-centered transitions of the acetal chromophore. The results are in agreement with an empirical CD-based assignment, which treated the acetal chromophore as two weakly coupled ether chromophores.