Tissue Plasminogen Activator in Pediatric Myocardial Infarction

Children rarely present to emergency physicians during an acute myocardial infarction. However, this may occur in the setting of Kawasaki disease with thrombosed coronary aneurysms. We present the first case in which intravenous tissue plasminogen activator was used to successfully treat a 7-year-old child having an acute myocardial infarction caused by a thrombosed coronary aneurysm. [Krendel S, Pollack P, Hanly J. Tissue plasminogen activator in pediatric myocardial infarction. Ann Emerg Med. May 2000;35:502-505.]