The effect of lethal doses of radiation in vivo on the lipid microviscosity of tumor nuclear membranes

The changes in the microviscosity of the nuclear membranes of tumor and liver cells of tumor hosts with developing Erlich ascites carcinoma at different times after irradiation of lethal doses has been studied by spin probe method. Using two iminoxyl radicals localized in various lipid regions, it was shown that the character and degree of changes in microviscosity, estimated from rotational correlation time for spin probes, indicate the differnt response to irradiation of liver and tumor cells.