Title of article
The synthesis of 191Pt labelled JM216, an orally active platinum anti-tumour agent
Author/Authors
P. I. Bates، نويسنده , , H. L. Sharma، نويسنده , , B. A. Murrer، نويسنده , , C. F. J. Bernard، نويسنده , , C. A. McAuliffe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
8
From page
469
To page
476
Abstract
The orally active platinum anti-tumour complex JM216 [bis-acetatoamminedichlorocyclohexylamineplatinum(IV)] is at present in stage II clinical trials. A procedure for synthesising the complex labelled with 191Pt or 188Pt at the platinum centre has been developed. The purity (shown by HPLC) is 98% and the specific activity (0.3–0.4 Ci/kg) is enough for in vivo and in vitro studies.
Journal title
Applied Radiation and Isotopes
Serial Year
1997
Journal title
Applied Radiation and Isotopes
Record number
539782
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