Title of article
Single-step synthesis of [18F]haloperidol from the chloro-precursor and its applications in PET imaging of a catʹs brain
Author/Authors
Kazunari Hashizume، نويسنده , , Hiroki Tamakawa، نويسنده , , Naoto Hashimoto، نويسنده , , Yoshihiro Miyake، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
7
From page
1179
To page
1185
Abstract
We have established a convenient synthesis process for the synthesis of [18F]haloperidol using a single-step 18F - for - Cl exchange reaction and a new elution system for the preparative high performance liquid chromatography (HPLC) using C18 bonded vinylalcohol copolymer gel (ODP) and a basic eluent. We successfully applied the product to cat-PET study and got clear images of the striatum, showing the usefulness of this synthesis.
Journal title
Applied Radiation and Isotopes
Serial Year
1997
Journal title
Applied Radiation and Isotopes
Record number
539892
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