Title of article :
Radiosynthesis of [123I]βCIT, a selective ligand for the study of the dopaminergic and serotoninergic systems in human brain
Author/Authors :
A. Carpinelli، نويسنده , , M. Matarrese، نويسنده , , R. M. Moresco، نويسنده , , P. Simonelli، نويسنده , , S. Todde، نويسنده , , G. Ferreres and J. F. Magni، نويسنده , , M. Galli Kienle، نويسنده , , F. Fazio، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
The procedure previously reported for the radiosynthesis of [123I]βCIT was modified in order to improve both radiochemical yield and purity of βCIT (2β-carbomethoxy-3β(4-iodophenyl) tropane) to be injected for SPECT (Single Photon Emission Computed Tomography) analysis imaging. The overall procedure, involving a HPLC purification step, results in quite good and reproducible yields of a highly purified tracer.
Keywords :
Radiosynthesis , Human brain , SPECT
Journal title :
Applied Radiation and Isotopes
Journal title :
Applied Radiation and Isotopes
