Author/Authors :
Seung-Jun Oh، نويسنده , , Dae-Hyuk Moon، نويسنده , , Hyun-Joon Ha، نويسنده , , Seong-Wook Park، نويسنده , , Myeong-Ki Hong، نويسنده , , Seung-Jung Park، نويسنده , , Tae Hyun Choi، نويسنده , , Sang-Moo Lim، نويسنده , , Chang Woon Choi، نويسنده , , F. F. (Russ) Knapp Jr.، نويسنده , , Hee-kyung Lee، نويسنده ,
Abstract :
We have developed an efficient method and an automated synthetic system for the preparation of highly concentrated 188Re–MAG3. Routine production of 188Re–MAG3 for use in intracoronary radiation therapy was performed by compressed air driven semi-automated shielded system. 188Re–MAG3 was prepared with a commercial kit and reducing agents, purified and concentrated by C18 Sep-Pak cartridges to desired radioactivity and volume. Using this automated system, reproducible radiolabeling yields of 80–85% were obtained.
