Monte Carlo dose parameters of the BrachySeed model LS-1 125I brachytherapy source

Using a modified EGS4 code and associated user code DOSCGC, the two-dimensional dose rate distribution in water and air-kerma strength are calculated for a BrachySeed (model LS-1) 125I brachytherapy source, based on geometry and material data provided by the manufacturer. The AAPM TG-43 dose parameters derived from these results include the dose rate constant, the radial dose function, the anisotropy function, and the anisotropy factor and constant. The value of the dose rate constant so obtained is 0.932±0.003 cGy h−1 U−1. The source strength calculation excludes the contribution from titanium characteristic X-rays (4.5 and 4.9 keV) in the source in order to comply with a new primary calibration standard implemented by the National Institute of Standards and Technology in 1999. A sampling procedure for simulating silver characteristic X-ray production in the mixture material of the source core is developed in the EGS4 code. The calculated results reveal the good dose isotropy of the LS-1 source. The Monte Carlo dose parameters obtained are compared with measurements and calculations of other investigators.