Title of article
Comparison of three different purification methods for the routine preparation of [11C] Metomidate
Author/Authors
Markus Mitterhauser، نويسنده , , Wolfgang Wadsak، نويسنده , , Oliver Langer، نويسنده , , Joern Schmaljohann، نويسنده , , Georg Zettinig، نويسنده , , Robert Dudczak، نويسنده , , Helmut Viernstein، نويسنده , , Kurt Kletter، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
125
To page
128
Abstract
PET with (R)-[O-methyl-11C] metomidate ([11C] MTO) is an attractive method for the characterisation of adrenal masses discriminating lesions of adrenal cortical origin from noncortical lesions. [11C] MTO was prepared by the reaction of [11C] methyliodide with the corresponding free acid. Three purification methods have been compared. The method of choice uses preparative HPLC with a ready-to-use weak acidic solvent.
Keywords
Preparation , 11?-hydroxylase , Purification
Journal title
Applied Radiation and Isotopes
Serial Year
2003
Journal title
Applied Radiation and Isotopes
Record number
541510
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