Author/Authors :
Markus Mitterhauser، نويسنده , , Wolfgang Wadsak، نويسنده , , Andreas Krcal، نويسنده , , Joern Schmaljohann، نويسنده , , Ewald Bartosch، نويسنده , , Harald Eidherr، نويسنده , , Helmut Viernstein، نويسنده , , Kurt Kletter، نويسنده ,
Abstract :
[11C]Acetate, initially developed for nuclear cardiology has gained increased interest also for oncological problems. A conjoint problem of all preparation methods is the high sensitivity of the Grignard-precursor to moisture, demanding long cleaning and drying procedures of apparatus and reaction vials. Our rationale was to simplify and accelerate the preparation of [11C]acetate by the development of an inert, sterile and disposable system. The present publication deals with the remote-controlled preparation of [11C]acetate via distillation into a buffer ready to use.
