Title of article
Alternative quality control for technetium-99m IDA complexes
Author/Authors
Mervyn W. Billinghurst، نويسنده , , Kellie Eckert، نويسنده , , Kennedy Mang’era، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
1151
To page
1155
Abstract
A quality control procedure for 99mTc-IDA complexes based on the use of C18 Sep-pakTM cartridges is developed and the validation of the procedure presented. C18 Sep-pakTM cartridges are pretreated by washing with 95% ethanol followed by 10−3 N hydrochloric acid. A small amount of the 99mTc-IDA complex is applied, washed with 10−3 N hydrochloric acid and eluted with 95% ethanol. The radiochemical purity values obtained for 99mTc-mebrofenin and 99mTc-disofenin using this Sep-pakTM procedure are comparable to those obtained using the standard two strip (ITLC-SG/100% methanol, ITLC-SA/20% saline) procedure.
Keywords
Mebrofenin , Disofenin , ITLC (instant thin layer chromatography) , Sep-pakTM , IDA(iminodiacetic acid) , 99mTc-technetium
Journal title
Applied Radiation and Isotopes
Serial Year
2004
Journal title
Applied Radiation and Isotopes
Record number
541888
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