Title of article
Production of the radioactive antitumoral cisplatin
Author/Authors
Alexandre S. Leal، نويسنده , , ?lvaro D. Carvalho J?nior، نويسنده , , Fabiana M. Abrantes، نويسنده , , Maria Angela de B.C. Menezes، نويسنده , , Vany Ferraz، نويسنده , , Tamara S. Cruz، نويسنده , , Valbert N. Cardoso، نويسنده , , Mônica C. de Oliveira، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
178
To page
181
Abstract
This work presents the preparation of radiolabelled cis-dichlorodiammineplatinum (II), CDDP*, sealed in a cadmium capsule. The irradiation of CDDP covered by cadmium, employing exposure times longer than 2 h, demonstrated good chemical purity and high specific activity. This finding allowed a better detection of in vivo CDDP* and suggests that it may be a good tool for studies of long-term biodistribution of pharmaceutical formulations containing this drug.
Keywords
TRIGA research reactor , Radiolabelled cisplatin , NEUTRON ACTIVATION
Journal title
Applied Radiation and Isotopes
Serial Year
2006
Journal title
Applied Radiation and Isotopes
Record number
547883
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