Author/Authors :
Seiji Nishino، نويسنده , , Beth Ripley، نويسنده , , Sebastiaan Overeem، نويسنده , , Gert Jan Lammers، نويسنده , , Emmanuel Mignot، نويسنده ,
Abstract :
Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission.