Author/Authors :
James Geiger، نويسنده , , Raymond Hutchinson، نويسنده , , Lyndon Hohenkirk، نويسنده , , Barry Smyth & Elizabeth McKenna، نويسنده , , Alfred Chang، نويسنده , , James Mulé، نويسنده ,
Abstract :
Dendritic cells are potent stimulators of antigen-specific immune responses, including antitumour responses. We explored the use of tumour-lysate-pulsed dendritic cells in children with relapsed solid tumours. Dendritic cell treatment in children was feasible and apparently not toxic. The treatment was able to produce significant tumour regression in a child with metatstatic fibrosarcoma.
